HYDROCORTISONE- hydrocortisone cream
E. Fougera & Co. a division of Fougera Pharmaceuticals Inc.
E. Fougera & Co. a division of Fougera Pharmaceuticals Inc.
This combination medication is used to treat irritation, soreness, and itchiness from certain skin conditions (e.g., scrapes, minor burns, eczema, insect bites). It can also be used to treat minor. This item 3-Pack Hydrocortisone 1% Anti-itch Cream - Compare to Cortaid - 0.5 Oz Tubes Hydrocortisone Maximum Strength Cream 1% with Aloe, 3 OZ (Compare to Cortizone-10) (3 x 1 OZ Tubes) Cortizone-10 Maximum Strength, 2 Ounce Box.
Disclaimer: Most OTC drugs are not reviewed and approved by FDA, however they may be marketed if they comply with applicable regulations and policies. FDA has not evaluated whether this product complies.
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Anti-itch
Uses:
- for temporary relief of itching associated with minor skin irritations and rashes due to:
- eczema
- insect bites
- soaps and detergents
- cosmetics
- jewelry
- seborrheic dermatitis
- psoriasis
- poison ivy , oak or sumac
- for external genital, feminine and anal itching
- other uses of this product should be only under the advice and supervision of a doctor
Warnings:
For external use only
Do not use
- in children under 2 years of age
- if you have a vaginal discharge
- for the treatment of diaper rash
Ask a doctor before use if you have
- external genital or feminine itching
- external anal itching
- bleeding
When using this product
- avoid contact with eyes
- do not exceed the recommended daily dosage unless directed by a doctor
- do not put this product into the rectum by using fingers or any mechanical device or applicator
Stop use and ask a doctor
- if condition worsens, or if symptoms persist for more than 7 days or clear up and occur again within a few days, stop use and do not begin use of any other hydrocortisone product
If swallowed, get medical help or contact a Poison Control Center right away.
Directions:
For minor skin irritations and rashes,
- adults and children 2 years of age and older: apply to affected area not more than 3 to 4 times daily .
Hydrocortisone 0.5% Cream Otc
For external anal itching:
- adults: when practical, cleanse the affected area with mild soap and warm water and rinse thoroughly
- gently dry by patting or blotting with toilet tissue or soft cloth before application of this product
- children: under 12 years of age, consult a doctor.
Other information:
Lidocaine 3% Hydrocortisone 0.5% Cream
- do not use if seal is punctured or is not visible. To open, reverse cap to puncture seal
- store at room temperature
- see crimp of tube for Lot Number and Expiration Date
Ipulse 3 0 5 Hydrocortisone Creamam Walgreens
benzyl alcohol, glycerin, glyceryl monostearate, isopropyl palmitate, lactic acid, paraffin, polyoxyl 40 stearate, potassium sorbate, purified water, sorbitan monostearate and stearyl alcohol.
Questions or comments? call toll free 1-800-645-9833
E. FOUGERA & CO.
A division of Fougera Pharmaceuticals Inc.
Melville, NY 11747
W5156B
R11/11
Fougera®
NDC 0168-0014-31
HYDROCORTISONE CREAM USP, 0.5%
ANTI-ITCH CREAM
NET WT 28.35g (1 Oz)
Fougera®
NDC 0168-0014-31
HYDROCORTISONE CREAM USP, 0.5%
ANTI-ITCH CREAM
![Cream Cream](https://www.isdin.com/sites/default/files/productos/imagenes/hidrocespuma_0.png?v=1400581958)
NET WT 28.35g (1 Oz)
HYDROCORTISONE hydrocortisone cream |
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Labeler - E. Fougera & Co. a division of Fougera Pharmaceuticals Inc. (043838424) |
Ipulse 3 0 5 Hydrocortisone Cream Usp
Set id: b600a0ef-104e-4051-9e48-9022eed5a7d9
![0.5 as a fraction 0.5 as a fraction](https://s.yimg.com/aah/yhst-135855760451349/zymox-topical-cream-with-0-5-hydrocortisone-1-oz-36.jpg)
Effective Time: 20120726
E. Fougera & Co. a division of Fougera Pharmaceuticals Inc.
MECHANISM OF ACTION:
Product releases lidocaine to stabilize the neuronal membrane by inhibiting the ionic fluxes required for initiation and conduction of impulses, thereby effecting local anesthetic action. Hydrocortisone acetate provides relief of inflammatory and pruritic manifestations of corticosteroid responsive dermatoses. Lidocaine is chemically designated as acetamide, 2-(diethylamino)-N-(2,6-dimethylphenyl), and has the following structure:
Hydrocortisone acetate has a chemical name pregn-4-ene-3, 20-dione, 21-(acetyloxy)-11,17- dihydroxy-(11ß)-. It has the following structural formula:
PHARMACOKINETICS:
Lidocaine may be absorbed following topical administration to mucous membranes, its rate and extent of absorption depending upon the specific site of application, duration of exposure, concentration, and total dosage. In general, the rate of absorption of local anesthetic agents following topical application occurs most rapidly after intratracheal administration. Lidocaine is also well-absorbed from the gastrointestinal tract, but little intact drug appears in the circulation because of biotransformation in the liver.
Lidocaine is metabolized rapidly by the liver, and metabolites and unchanged drug are excreted by the kidneys. Biotransformation includes oxidative N-dealkylation, ring hydroxylation, cleavage of the amide linkage, and conjugation. N-dealkylation, a major pathway of biotransformation, yields the metabolites monoethylglycinexylidide and glycinexylidide. The pharmacological/toxicological actions of these metabolites are, similar to but less potent than, those of lidocaine. Approximately 90% of lidocaine administered is excreted in the form of various metabolites, and less than 10% is excreted unchanged. The primary metabolite in urine is a conjugate of 4-hydroxy-2, 6-dimethylaniline. The plasma binding of lidocaine is dependent on drug concentration, and the fraction bound decreases with increasing concentration. At concentrations of 1 to 4 g of free base per mL, 60 to 80 percent of lidocaine is protein bound. Binding is also dependent on the plasma concentration of the alpha-1-acid glycoprotein. Lidocaine crosses the blood-brain and placental barriers, presumably by passive diffusion.
0-5 Military Rank
Studies of lidocaine metabolism following intravenous bolus injections have shown that the elimination half-life of this agent is typically 1.5 to 2 hours. Because of the rapid rate at which lidocaine is metabolized, any condition that affects liver function may alter lidocaine kinetics. The half-life may be prolonged two-fold or more in patients with liver dysfunction. Renal dysfunction does not affect lidocaine kinetics but may increase the accumulation of metabolites. Factors such as acidosis and the use of CNS stimulants and depressants affect the CNS levels of lidocaine required to produce overt systemic effects. Objective adverse manifestations become increasingly apparent with increasing venous plasma levels above 6 g free base per mL. In the rhesus monkey arterial blood levels of 18-21 g/mL have been shown to be threshold for convulsive activity.
The extent of percutaneous absorption of topical corticosteroids is determined by many factors including the vehicle, the integrity of the epidermal barrier, and the use of occlusive dressings.
2.5 % Hydrocortisone Cream
Topical corticosteroids can be absorbed from normal intact skin. Inflammation and/or other disease processes in the skin increase percutaneous absorption. Occlusive dressings substantially increase the percutaneous absorption of topical corticosteroids. Thus, occlusive dressings may be a valuable therapeutic adjunct for treatment of resistant dermatoses.
Impulse 3 0 5 Hydrocortisone Cream Rocortisone Cream Uses
Once absorbed through the skin, topical corticosteroids are handled through pharmacokinetic pathways similar to systemically administered corticosteroids. Corticosteroids are bound to plasma protein in varying degrees. Corticosteroids are metabolized primarily in the liver and are then excreted by the kidneys. Some of the topical corticosteroids and their metabolites are also excreted into the bile.